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There are a total of 11 playable characters in The Binding of Isaac: Rebirth

For details about every stat check Stats

Character Health
HeartIcon
Speed
SpeedIcon
Tears Shot Speed Attack
AttackIcon
Range Luck

Starting Items

Info

Biblical reference

Isaac
Isaac
3 2 2 2 2

x1 Bomb

The Dice (unlocked after beating The Womb with ???)

Default, first character.

The son of Abraham whom God asked to sacrifice in Binding of Isaac.

Maggy
Magdalene
4 1 2 2 2

Yum Heart

Unlocked by having seven or more Heart Containers in one playthrough (Soul Hearts do not count).

One of Jesus' friends. Also known as Mary.
Cain
Cain
2 3 2 3 1

x1 Key

Lucky Foot

Unlocked by having 55 or more coins at any one time in one playthrough.

Son of Adam and Eve, brother of Abel. Was the first murderer and murdered Abel.
Judas
Judas
1 2 2 4 2

x3 Penny

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The Book Of Belial

Unlocked after defeating Satan for the first time.

Judas Iscariot, the one who betrayed Jesus Christ.
Eve
Eve
2 3 2 1 2

Dead Bird

Whore Of Babylon

Unlocked by going through two floors without picking up heart drops.

First female created by God and the first sinner.
BlueBaby
???
N/A 2 2 2 2

x3 Soul Hearts

SoulHeartSoulHeartSoulHeart

The Poop

Unlocked after defeating It Lives.

Can not have hearts. Items that would normally increase max health add Soul Hearts instead. Normal heart pickups and healing has no effect.

None (Reference to Edmund McMillen)

Samson
Samson

3 2 2 2 2

Bloody Lust

Unlocked by going through two floors without taking damage 

He was born into the world by God to defeat the Philistines, but had his hair cut off because it was one of the three sources of his power (along with not drinking wine and not approaching carcasses). He lost his power, was captured and blinded after revealing his secret.
Azazel
Azazel
N/A

x3 Black Hearts

Black Heart containerBlack Heart containerBlack Heart container

Unlocked by making 3 deals with the devil in a Single run

Capable of gaining Red Heart containers, unlike ???.

Starting tears are a short-ranged version of Brimstone.

Hebrew word for "scapegoat," or sometimes understood as "demon" or "fallen angel". In the Bible, a goat marked "for Azazel" had the sins of the people ritually placed on it, then was taken out to the desert and left there.
Lazarus
Lazarus
3

Unlocked by obtaining 4 soul hearts in a single run

Able to resurrect one time, staying in the room he died in with a single red heart.

A friend of Jesus who died and was resurrected by Jesus, walking out of his tomb at Jesus' command, still wrapped in his burial bandages.
Eden
Eden
Random Random Random Random Random Random Random Random Unlocked by beating Mom's Heart for the first time. Requires Eden tokens to play. The garden in which Adam and Eve first lived which contained the Tree of Life and the Tree of the Knowledge of Good and Evil. After Adam and Eve were evicted, an angel with a flaming sword was placed at the entrance of Eden to stop anyone else from entering.
The Lost N/A


Playable Characters
Isaac Scribble
Isaac
Magdalene scribble
Magdalene
Cain scribble
Cain
Judas scribble
Judas
Eve scribble
Eve
BlueBaby scribble
???
Samson scribble
Samson
Azazel scribble
Azazel
Lazarus scribble
Lazarus
Eden scribble
Eden
45px
The Lost

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